On this page
- About the NBME lab values sheet
- How the NBME sheet is organised
- The high-yield values to know by heart
- Unit traps on exam questions
- Calculations that build on NBME values
- Classic lab patterns worth recognising
- How exam ranges differ from real-world ranges
- Exam-day tips for using the lab values
- Frequently asked questions
About the NBME lab values sheet
The NBME Laboratory Reference Values sheet is the standard table of "normal" lab values provided during USMLE Step 1, Step 2 CK and Step 3, NBME subject (shelf) exams and NBME self-assessments. Whenever a question gives you a laboratory result, you can open the lab values reference to compare it with the range – so knowing how the sheet is laid out and which values matter most saves real time on exam day.
The searchable table above reproduces the values from the NBME's current published sheet (April 2026 version) in both conventional (US) units and SI units. Type any analyte – "ferritin", "PTT", "CSF glucose", "cortisol" – to filter instantly. Below, you will find how the sheet is organised, which ranges are most worth memorising, common traps with units, and how the NBME ranges compare with what you will see on real clinical reports.
Important: these are exam reference values. Real laboratories set their own reference intervals, which can differ. For interpreting your own blood test, use the range on your report – our how to read a blood test guide explains how.
How the NBME sheet is organised
The sheet groups analytes by specimen and system. Knowing the order means you can jump straight to the right section:
| Section | What it contains | Examples |
|---|---|---|
| Serum – general chemistry | Electrolytes, kidney, glucose, minerals | Na, K, Cl, HCO₃, BUN, creatinine, glucose, Ca, Mg, phosphorus |
| Serum – hepatic | Liver enzymes and proteins | ALT, AST, ALP, bilirubin, total protein, albumin, globulin |
| Serum – other | Pancreas, muscle, misc. | Amylase, lipase, CK, LDH, osmolality, troponin I, uric acid, creatinine clearance |
| Lipids | Cholesterol fractions | Total, HDL, LDL, triglycerides |
| Iron studies | Iron panel | Ferritin, iron, TIBC, transferrin |
| Endocrine | Pituitary, thyroid, adrenal, PTH | FSH, LH, prolactin, cortisol, TSH, T3, T4, free T4, PTH |
| Immunoglobulins | IgA, IgE, IgG, IgM | |
| Arterial blood gases | Room air | pH, Pco₂, Po₂ |
| Cerebrospinal fluid | Lumbar puncture | Cell count, glucose, protein, pressure |
| Haematologic | CBC and differential, volumes | Hb, Hct, MCV, MCH, MCHC, WBC, differential, platelets |
| Coagulation and other haematologic | Clotting, reticulocytes, ESR | PT, PTT, D-dimer, reticulocyte count, RBC count, ESR, CD4 |
| Urine and BMI | 24-hour urine values, BMI | Urine calcium, osmolality, oxalate, protein; adult BMI |
The high-yield values to know by heart
You can always look values up, but every click costs time – and many questions hinge on recognising an abnormal value instantly. These are the ranges most worth memorising:
| Analyte | NBME range | Why it is high-yield |
|---|---|---|
| Sodium | 136–146 mEq/L | Hypo/hypernatraemia, SIADH, diabetes insipidus |
| Potassium | 3.5–5.0 mEq/L | ECG changes, renal tubular acidosis, diuretics |
| Chloride | 95–105 mEq/L | Anion gap, contraction alkalosis |
| Bicarbonate | 22–28 mEq/L | Acid–base questions |
| BUN | 7–18 mg/dL | Pre-renal vs intrinsic AKI (BUN/Cr ratio) |
| Creatinine | 0.6–1.2 mg/dL | Kidney function |
| Glucose (fasting) | 70–100 mg/dL | Diabetes, hypoglycaemia, insulinoma |
| Calcium | 8.4–10.2 mg/dL | Hyperparathyroidism, malignancy |
| Magnesium | 1.5–2.0 mg/dL | Refractory hypokalaemia |
| Phosphorus | 3.0–4.5 mg/dL | CKD-mineral bone disease, hypoparathyroidism |
| ALT / AST | 10–40 / 12–38 U/L | Hepatitis patterns, AST:ALT ratio |
| Haemoglobin | M 13.5–17.5 / F 12.0–16.0 g/dL | Anaemia |
| MCV | 80–100 fL | Classifying anaemia |
| WBC | 4,500–11,000/mm³ | Infection, leukaemia |
| Platelets | 150,000–400,000/mm³ | ITP, TTP, HIT, DIC |
| PT / PTT | 11–15 / 25–40 s | Coagulation pathway questions |
| ABG pH / Pco₂ | 7.35–7.45 / 33–45 mm Hg | Acid–base compensation |
| TSH | 0.4–4.0 µU/mL | Thyroid disease |
| HbA1c | ≤ 6% | Diabetes |
A good habit is to know these well enough that you only open the sheet for less common values – CSF, immunoglobulins, urine studies and hormones.
Unit traps on exam questions
Most USMLE questions use conventional units, but values are sometimes given in SI units, and the sheet shows both. Common pitfalls:
- Haemoglobin in g/L vs g/dL – 120 g/L is 12.0 g/dL.
- Glucose in mmol/L – multiply by about 18 to get mg/dL (5.6 mmol/L ≈ 100 mg/dL).
- Creatinine in µmol/L – divide by 88.4 to get mg/dL (106 µmol/L ≈ 1.2 mg/dL).
- Blood gases in kPa – multiply by 7.5 to get mm Hg (5.3 kPa ≈ 40 mm Hg).
- WBC and platelets – "/mm³" and "× 10⁹/L" differ by a factor of 1,000: 11,000/mm³ = 11.0 × 10⁹/L.
- TSH – µU/mL and mIU/L are numerically identical.
If you want to practise conversions, the lab unit converter and mg/dL to mmol/L converter cover the main analytes, and the mg/dL to µmol/L converter handles creatinine, uric acid and bilirubin.
Calculations that build on NBME values
Several exam favourites are derived from values on the sheet rather than listed on it:
| Calculation | Formula | Normal | Tool |
|---|---|---|---|
| Anion gap | Na − (Cl + HCO₃) | About 8–12 mEq/L | Anion gap calculator |
| Serum osmolality | 2 × Na + glucose/18 + BUN/2.8 | 275–295 mOsm/kg | Osmolality calculator |
| Corrected calcium | Ca + 0.8 × (4 − albumin) | 8.4–10.2 mg/dL | Corrected calcium |
| BUN/creatinine ratio | BUN ÷ Cr | About 10–20 | BUN/creatinine ratio |
| Corrected sodium (hyperglycaemia) | Na + 1.6 to 2.4 × (glucose − 100)/100 | – | Corrected sodium |
| Transferrin saturation | Iron ÷ TIBC × 100 | About 20–50% | TIBC blood test |
| QTc | QT ÷ √RR (Bazett) | Under about 450 ms (men), 460 ms (women) | QTc calculator |
| A–a gradient | PAo₂ − Pao₂ | Rises with age | – |
Classic lab patterns worth recognising
Many exam questions hinge on a combination of values rather than any single result. A few classic patterns that use the ranges on the sheet:
| Pattern | Key values | Typical association |
|---|---|---|
| High anion gap metabolic acidosis | Low HCO₃, gap above about 12 | Ketoacidosis, lactic acidosis, kidney failure, toxic alcohols, salicylates |
| Contraction (metabolic) alkalosis | High HCO₃, low Cl, low K | Vomiting, diuretics |
| SIADH | Low Na, low serum osmolality, inappropriately concentrated urine | Small-cell lung cancer, CNS disease, some medicines |
| Primary hyperparathyroidism | High Ca, high or inappropriately normal PTH, low phosphorus | Parathyroid adenoma |
| Microcytic anaemia with low ferritin | Low Hb, MCV under 80, low ferritin, high TIBC | Iron deficiency |
| Haemolysis | Low Hb, high reticulocytes, high LDH, high indirect bilirubin | Autoimmune, G6PD, hereditary spherocytosis |
| Isolated prolonged PT | PT above 15 s, normal PTT | Warfarin, early vitamin K deficiency, liver disease |
| Isolated prolonged PTT | PTT above 40 s, normal PT | Haemophilia A/B, heparin, lupus anticoagulant |
| Bacterial meningitis CSF | High cells (neutrophils), low glucose, high protein | Compare with CSF reference values |
Recognising these combinations quickly is far more valuable than recalling an isolated number.
How exam ranges differ from real-world ranges
The NBME values are designed to be consistent, simple and stable across exams. Real laboratories differ in several ways:
| Analyte | NBME sheet | Common clinical practice | Note |
|---|---|---|---|
| Creatinine | 0.6–1.2 mg/dL (single range) | Sex-specific ranges (e.g. MedlinePlus 0.7–1.3 men, 0.5–0.95 women) | eGFR is used clinically |
| HbA1c | ≤ 6% | Under 5.7% normal; 5.7–6.4% prediabetes; 6.5%+ diabetes (ADA) | Diagnostic thresholds |
| LDL | < 160 mg/dL | Risk-based targets | Guidelines use overall cardiovascular risk |
| Ferritin (women) | 10–120 ng/mL | Many clinicians treat under 30 as iron deficiency | Thresholds vary by context |
| TSH | 0.4–4.0 | Upper limits up to 4.5–5.0; age-dependent | Pregnancy uses trimester ranges |
| Troponin I | ≤ 0.04 ng/mL | High-sensitivity assays with sex-specific 99th centiles in ng/L | Assay-dependent |
| BMI | Adult 19–25 kg/m² | WHO normal 18.5–24.9 kg/m² | Rounded on the sheet |
So for clinical work, always use your local laboratory's ranges and current guidelines. For exams, use the sheet.
Exam-day tips for using the lab values
- Practise with the sheet open during question banks so you know where each value sits.
- Learn the high-yield ranges above so you only need the sheet for rarer values.
- Use the search box on the exam interface rather than scrolling; on this page, the search above behaves similarly.
- Read the units in the question stem before comparing with the sheet.
- Do not over-interpret borderline values – exam questions usually make significant abnormalities obvious.
- Remember derived values: an anion gap or A–a gradient is rarely given directly.
Frequently asked questions
Do you get lab values on USMLE Step 1?
Yes. A laboratory reference values table is available during USMLE exams and NBME exams, accessible from the exam interface.
Are the NBME lab values the same for Step 1, Step 2 CK and Step 3?
The NBME publishes one laboratory reference values sheet used across its exams. The values on this page follow the current published version.
Should I memorise normal lab values for Step 1?
Memorising the high-yield values – electrolytes, kidney function, glucose, calcium, CBC, coagulation and ABG – saves time. Rarer values can be looked up.
Is the NBME lab sheet the same as real clinical ranges?
No. The sheet is simplified for exams. Real laboratories use their own reference intervals, and some tests, such as HbA1c and LDL, are interpreted with guideline thresholds.
What is the normal anion gap on the NBME?
The anion gap is not listed on the sheet; it is calculated as Na − (Cl + HCO₃). With NBME values, a typical gap is about 8–12 mEq/L.
What is the NBME normal range for HbA1c?
The sheet lists HbA1c as ≤ 6% (≤ 42 mmol/mol). Clinically, the ADA defines 5.7–6.4% as prediabetes and 6.5% or more as diabetes – see the [A1C calculator](/a1c-calculator).
Are the NBME values in SI units too?
Yes, for most tests. The NBME sheet lists most analytes in conventional (US) units with SI equivalents alongside, so you can practise reading both systems, which is useful if you plan to train or work outside the US. The [lab unit converter](/lab-unit-converter) shows the conversion factors.
What BMI does the NBME list as normal?
Adult 19–25 kg/m². The WHO definition of a normal BMI is 18.5–24.9 kg/m² – see the [BMI calculator](/bmi-calculator).